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3.
Enferm Infecc Microbiol Clin ; 26(8): 510-7, 2008 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-19094866

RESUMO

Vertebral osteomyelitis or spondylodiscitis is an uncommon, mainly hematogenous, disease that usually affects adults. The incidence of this condition has steadily risen in recent years because of increases in spine surgery and nosocomial bacteremia, aging of the population, and intravenous drug addiction. Pyogenic infection due to Staphylococcus aureus is the most frequent form of the disease, but tuberculosis and brucellosis are still common causes of spondylitis in Spain. The clinical presentation is nonspecific and the diagnosis is often delayed. Magnetic resonance imaging is the most sensitive radiologic technique for this disease. Blood cultures are often positive, but computed tomography-guided needle biopsy or surgical biopsy of the affected vertebra is sometimes required to achieve a microbiological diagnosis. Prolonged antibiotic therapy and occasionally surgery are essential for cure in most patients, and both factors have contributed to a reduction in the morbidity and mortality of the disease in recent years.


Assuntos
Artrite Infecciosa , Osteomielite , Espondilite , Algoritmos , Antibacterianos/uso terapêutico , Artrite Infecciosa/diagnóstico , Artrite Infecciosa/epidemiologia , Artrite Infecciosa/microbiologia , Artrite Infecciosa/terapia , Brucelose/diagnóstico , Brucelose/epidemiologia , Brucelose/terapia , Terapia Combinada , Infecção Hospitalar/diagnóstico , Infecção Hospitalar/epidemiologia , Infecção Hospitalar/microbiologia , Infecção Hospitalar/terapia , Desbridamento , Diagnóstico por Imagem , Discite/diagnóstico , Discite/epidemiologia , Discite/microbiologia , Discite/terapia , Drenagem , Humanos , Osteomielite/diagnóstico , Osteomielite/epidemiologia , Osteomielite/microbiologia , Osteomielite/terapia , Prognóstico , Espanha/epidemiologia , Fusão Vertebral , Espondilite/diagnóstico , Espondilite/epidemiologia , Espondilite/microbiologia , Espondilite/terapia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/epidemiologia , Infecções Estafilocócicas/terapia , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/terapia , Tuberculose da Coluna Vertebral/diagnóstico , Tuberculose da Coluna Vertebral/epidemiologia , Tuberculose da Coluna Vertebral/terapia
4.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 26(8): 510-517, oct. 2008. ilus, tab
Artigo em Es | IBECS | ID: ibc-70016

RESUMO

La osteomielitis vertebral o espondilodiscitis es una enfermedad poco frecuente que suele afectar a adultos. Su incidencia ha aumentado en los últimos años debido a la mayor frecuencia de procedimientos quirúrgicos espinales y de bacteriemia nosocomial, el envejecimiento de la población y la adicción a drogas intravenosas. La infección hematógena es la causa más común de espondilitis. La infección piógena, producida por Staphylococcus aureus, es la forma más frecuente de enfermedad, aunque la tuberculosis y la brucelosis son todavía una etiología frecuente en nuestro país. La presentación clínica es inespecífica, lo que condiciona un gran retraso diagnóstico. La resonancia magnética es la técnica de imagen más sensible. Los hemocultivos son, con frecuencia, positivos, pero suele ser necesaria la biopsia vertebral quirúrgica o guiada por tomografía para conseguir el diagnóstico microbiológico. El tratamiento antibiótico prolongado y ocasionalmente la cirugía son esenciales para conseguir la curación en la mayoría de los enfermos y ambos factores han contribuido a la reducción de su morbimortalidad en los últimos años (AU)


Vertebral osteomyelitis or spondylodiscitis is an uncommon, mainly hematogenous, disease that usually affects adults. The incidence of this condition has steadily risen in recent years because of increases in spine surgery and nosocomial bacteremia, aging of the population, and intravenous drug addiction. Pyogenic infection due to Staphylococcus aureus is the most frequent form of the disease, but tuberculosis and brucellosis are still common causes of spondylitis in Spain. The clinical presentation is nonspecific and the diagnosis is often delayed. Magnetic resonance imaging is the most sensitive radiologic technique for this disease. Blood cultures are often positive, but computed tomography-guided needle biopsy or surgical biopsy of the affected vertebra is sometimes required to achieve a microbiological diagnosis. Prolonged antibiotic therapy and occasionally surgery are essential for cure in most patients, and both factors have contributed to a reduction in the morbidity and mortality of the disease in recent years (AU)


Assuntos
Humanos , Espondilite/microbiologia , Infecções Estafilocócicas/microbiologia , Osteomielite/microbiologia , Discite/microbiologia , Staphylococcus aureus/patogenicidade , Antibacterianos/uso terapêutico
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